Description
POLYSORBATE 80
Polysorbate 80 is a nonionic surfactant and emulsifier commonly used in the food, cosmetic, and pharmaceutical industries. It’s a synthetic compound that is a viscous, water-soluble yellow liquid. It is also known by the brand name Tween 80.Polysorbate 80’s primary function is to help mix ingredients that don’t normally blend well, such as oil and water. Its molecular structure has both a water-loving (hydrophilic) head and an oil-loving (hydrophobic) tail, allowing it to act as a bridge between the two.
Chemical Properties
| Property | Details |
|---|---|
| Product Name | Polysorbate 80 |
| INCI Name | Polysorbate 80 |
| Chemical Name | Polyoxyethylene (20) sorbitan monooleate |
| Chemical Type | Non-ionic surfactant / emulsifier |
| CAS Number | 9005-65-6 |
| Molecular Weight | ~1310 g/mol (average) |
| Appearance | Amber to brownish viscous liquid |
| Odor |
Polysorbate 80 (also known as Tween 80) is a nonionic surfactant and emulsifier commonly used in a wide range of industries. Here are its main uses, grouped by category:
1.Pharmaceutical and Medical Uses
Emulsifier in injectable formulations, vaccines (e.g., flu vaccines), and IV preparations.
Solubilizer for drugs that are poorly water-soluble.
Stabilizer in protein-based drugs and biologics.
Used in eye drops, topical creams, and lotions.
2. Food Industry
Emulsifier in salad dressings, sauces, desserts, and ice cream.
Prevents separation of oil and water components.
Helps improve texture and shelf life of baked goods.
Food additive labeled as E433.
3. Cosmetic and Personal Care Products
Used in lotions, creams, shampoos, and conditioners.
Helps blend oil and water-based ingredients.
Improves product stability and texture.
4. Laboratory and Industrial Applications
Used in cell culture media to stabilize proteins or membranes.
Component in microbiological media for cultivating certain bacteria.
Used in nanoparticle preparation and drug delivery research.
Acts as a wetting agent or dispersant in some industrial processes.
Other Applications
Occasionally used in cleaning products and some textile treatments.







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