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Dextrose anhydrous

Dextrose anhydrous is a highly purified, crystalline form of glucose used widely in pharmaceuticals, food, and biotechnology. It serves as an energy source, excipient, and stabilizer thanks to its excellent solubility and stability.

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Description

Dextrose anhydrous is a simple sugar, also known as D-glucose. The term “anhydrous” indicates that it does not contain any water molecules in its crystalline structure, differentiating it from dextrose monohydrate, which contains one molecule of water of crystallization. It is a white, crystalline powder that is odorless, has a sweet taste, and is freely soluble in water.


Key Properties and Uses

Property Description
Chemical name D-Glucose (Anhydrous)
Chemical formula C₆H₁₂O₆
Molecular weight 180.16 g/mol
Appearance White crystalline powder
Odor Odorless
Taste Sweet
Solubility Highly soluble in water; slightly soluble in alcohol
Melting point ~146°C (decomposes)
Density ~1.54 g/cm³ (crystalline)
Optical activity Dextrorotatory (+52.7° solution)
Hygroscopicity Hygroscopic; absorbs moisture from air
pH (aqueous solution) ~4.0–6.0
Stability Stable under dry conditions; decomposes on prolonged heating
Chemical nature Reducing sugar (can undergo Maillard reaction and caramelization)

 


Uses 

Pharmaceuticals: In the medical field, it’s used to prepare intravenous solutions (IVs) for patients who cannot consume food or need to restore fluid balance and energy. It’s also a common excipient (inactive ingredient) in tablets and other medications, serving as a filler, binder, or sweetener.

Food and Beverage Industry: It’s used as a sweetener, a source of carbohydrates, and a bulking agent. Its applications include baked goods, candy, energy drinks, and processed foods.

Athletic Nutrition: Due to its rapid absorption, dextrose anhydrous is a popular ingredient in sports drinks and supplements to quickly replenish muscle glycogen after intense exercise.

Animal Feed: It is a valuable source of energy and a nutritional supplement in animal feed for livestock and pets.


Dextrose Anhydrous vs. Dextrose Monohydrate

Dextrose Anhydrous (C6​H12​O6​): Contains no water molecules. It is typically a purer product with a higher concentration of glucose by weight. This makes it more suitable for applications where moisture is a concern, such as in certain pharmaceutical formulations or for specialized industrial uses.

Dextrose Monohydrate (C6​H12​O6​⋅H2​O): Contains one molecule of water per molecule of dextrose. It is more commonly used in food and beverage products as a sweetener and is generally less expensive to produce. It’s also widely used in various nutritional products and as a fermentation substrate

 

 

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